The mission of International Society for Mathematics and Science Education (ISMSE) is to share the wisdom of many researchers who study the mathematics and science education for developing the capability of all children in the world. We are serious about future education in the 2050. Currently, in the lesson of mathematics and science, it is important that children understand the learning contents and the meaning of the contents deeply, and acquire the competence and ability of being able to discover a new idea and creates new knowledge in problem solving. How will these ideas progress in the future? We strive and expect that all children in the world will study mathematics and science freshly and will grow up as a creative human by collaborations and efforts of you, ISMSE members.